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所在位置:所有产品 > 抗体抗原 > 一抗 > RALA抗体
RALA抗体图片
产品货号:
Z24999
中文名称:
RALA抗体
英文名称:
Anti-RALA Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-RALA Antibody
指标别名RAL;RALA;Ras related protein Ral A
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB
基因名称RALA
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human RALA (165-203aa DKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERC),identical to the related mouse and rat sequences.
实际分子量24KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Ras-related protein Ral-A (RalA) is a protein that in humans is encoded by the RALA gene on chromosome 7.This protein is one of two isoforms of the Ral protein,the other being RalB,and part of the Ras GTPase family.As a Ras GTPase,RalA functions as a molecular switch that becomes active when bound to GTP and inactive when bound to GDP.It can be activated by RalGEFs and,in turn,activate effectors in signal transduction pathways leading to biological outcomes.Additionally,Ral proteins have been associated with the progression of several cancers,including bladder cancer and prostate cancer.While the above functions appear to be shared between the two Ral isoforms,their differential subcellular localizations result in their differing involvement in certain biological processes.In particular,RalA is more involved in anchorage-independent cell growth,vesicle trafficking,and cytoskeletal organization.Moreover,RalA specifically interacts with Exo84 and Sec5 to regulate transport of membrane proteins in polarized epithelial cells and GLUT4 to the plasma membrane,as well as mitochondrial fission for cell division.
Uniprot IDP11233
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称v-ral simian leukemia viral oncogene homolog A (ras related)
蛋白名全称Ras-related protein Ral-A
推荐稀释比
Western blot(WB) 1:500~2000

相关搜索:RALA抗体RALA多抗Anti-RALA Antibody
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